Building Eminence through Evidence

Evidence, eminence and extrapolation

A full independent drug development programme to demonstrate efficacy may not be ethical and/or feasible in small populations such as paediatric populations or orphan indications. Different levels of extrapolation from a larger population to smaller target populations are widely used for supporting decisions in this situation. There are guidance documents in drug regulation, where a weakening o...

Building up original evidence

American researchers are unfamiliar. Even when Japanese contributions are just as good as those from America, the journals have no choice but to allot their space to the latter. If Japanese researchers want to report their own research overseas in the same fields as ours, then Japanese academic societies will have to publish their own journals in English.” World-famous academic journals in Engl...

Building practice-based evidence.

Building strength through partnerships.

the fall 2003 conference and annual meeting held in Ottawa in September. As we move forward, our work continues to be shaped by the vision of the Academy: to become a national voice for executive nurse leaders, to influence and participate in direction setting for healthcare policy, to contribute to the alignment and advancement of the national nursing agenda and to develop strong strategic coa...

Tibial eminence fractures.

Tibial eminence fracture, a bony avulsion of the anterior cruciate ligament (ACL) from its insertion on the intercondylar eminence, was first described by Poncet in 1875. Also known as tibial spine fractures, these injuries occur most commonly in skeletally immature patients between the ages of 8 and 14 years. They account for 2% to 5% of knee injuries in the pediatric population and 14% of ACL...